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Neag Comprehensive Cancer Center

Ovarian Cancer

What Is Ovarian Cancer?

Ovarian cancer is a relatively rare cancer found in one or both ovaries. Ovarian cancer accounts for about 3 percent of all cases of cancer in women.

In its early stages, ovarian cancer often presents with no symptoms, making it difficult to diagnose. When it's found early and limited to the ovaries, there’s a 90 to 95 percent chance the patient will survive long-term. The five-year survival rate is less when it is detected at an advanced stage.

The best precaution is to have a yearly pelvic exam by a physician who is aware of your family and medical history. It is especially important for your doctor to be aware of any factors that place you at higher risk for this disease.

Some factors that could increase a woman’s chances of developing ovarian cancer are:

  • Being over 60 years of age
  • Having a family history of ovarian, breast, or colorectal cancer
  • Having inherited mutations of the BRCA1 or BRCA2 genes
  • Having a history of infertility or not having had a child

Symptoms

The symptoms of ovarian cancer are subtle and may include:

  • Abdominal swelling, bloating
  • Indigestion
  • Vague but persistent gastrointestinal complaints
  • Frequent urination
  • Menstrual disorders such as abnormal bleeding or postmenopausal bleeding

Diagnosis

Women at higher risk can take advantage of frequent screening tests, including a transvaginal ultrasound of the ovaries and, in some cases, blood tests. Counseling and prevention strategies for women at higher risk are available at the Carole and Ray Neag Comprehensive Cancer Center. This may also involve a referral to a genetic counselor to consider genetic testing to determine if you have a mutation that predisposes you to ovarian cancer.

If cancer is suspected, exploratory surgery may be done so the doctor can see the ovaries and take tissue samples. If tests of the samples reveal cancer, then appropriate surgery is the initial phase of treatment, after which chemotherapy may be used.

Ovarian cancer is determined, but we are even more determined. Our researchers are working on a therapeutic vaccine aimed at eliminating the recurrence of ovarian cancer.

What Women Need To Know about Ovarian Cancer

The Julie Merle Epstein Cancer Fund

  • What Is Ovarian Cancer?

    The ovaries are the organs that produce a woman’s eggs. Like many other parts of the body, they are susceptible to cancer, a condition in which cells grow in an uncontrolled fashion.

  • Just How Common Is Ovarian Cancer?

    It is relatively rare, accounting for about 3 percent of all cases of cancer in women. In general, your chances of getting ovarian cancer are 1 in 58 (compared to 1 in 7 for breast cancer), but the odds worsen as various risk factors are considered.

  • Why Should I Worry About Ovarian Cancer?

    You shouldn’t worry about it – but you should be aware of it and take the steps to detect it at a stage when the chance of a cure is high. When this cancer is found early and in still in the ovaries, there’s a 90 to 95 percent chance the patient will survive five years. When it is detected at an advanced stage, the five-year survival rate drops to 18 percent.

  • At What Age Is Ovarian Cancer Most Likely To Be Found?

    It is most often found in women between the ages of 40 and 70 – and women between 50 and 59 are in the high-risk group – but it sometimes strikes women in their 20s. In fact, the Julie Merle Epstein Cancer Fund at UConn Health was created to honor the memory of Julie, a woman who died from ovarian cancer at the age of 28.

  • I Have a Pap Test Each Year. Will It Detect Ovarian Cancer?

    No. The Pap test detects cancer of the cervix, not cancer of the ovaries.

  • What Should I Do To Detect Ovarian Cancer?

    The best precaution is to have a complete pelvic exam done every year by a physician who is aware of your family and medical history. It is especially important for your doctor to be aware of any factors that place you at high risk for this disease.

  • What Are the Risk Factors for Ovarian Cancer?

    The most important is a family history of ovarian cancer – a mother, sister, or grandmother who had it. A history of breast or colorectal cancer increases your risk, as does infertility or never having given birth to a living child. The use of birth control pills or having several children is associated with a lower risk for ovarian cancer.

  • Are There Warning Signals To Watch For?

    The symptoms of ovarian cancer are subtle. It is called the “disease that whispers,” meaning there are no obvious signs and symptoms until the disease has advanced. Then, the symptoms may be:

    • Abdominal swelling, bloating
    • Indigestion
    • Vague but persistent gastrointestinal complaints
    • Frequent urination
    • Menstrual disorders such as abnormal bleeding or postmenopausal bleeding
  • Services for Women at Higher Risk

    Although researchers are trying to find ways to identify “tumor markers” (substances in the blood or urine that may reveal cancer before symptoms develop), there currently is no screening exam to detect this cancer in women without symptoms.

    However, women at higher risk can take advantage of frequent screening tests, including transvaginal ultrasound of the ovaries and in some cases, blood tests. Counseling and prevention strategies for women at higher risk are available at the Carole and Ray Neag Comprehensive Cancer Center.

  • How Is Ovarian Cancer Diagnosed & Treated?

    If cancer is suspected, exploratory surgery may be done so the doctor can see the ovaries and take tissue samples. If tests of the samples reveal cancer, then appropriate surgery is the initial phase of treatment, after which chemotherapy may be used.

  • Risk Factors for Ovarian Cancer

    A woman with one or more of the following characteristics may be at above-average risk for ovarian cancer. She should make sure her physician is aware of her risk factors.

    • Family history of ovarian cancer (mother, aunt, sister, grandmother)
    • History of breast cancer or colorectal cancer
    • Never having given birth to an infant who survived
    • Infertility
    • Increasing age
    • Jewish ancestry

    This resource was made possible through generous support from the Julie Merle Epstein Cancer Fund.

UConn Health, an AAGL Center of Excellence

We are committed to offering minimally invasive surgery, which includes advanced laparoscopic, vaginal, and abdominal approaches to complex gynecologic conditions and malignancies. Our providers are faculty within the COEMIG Center of Excellence for minimally invasive gynecology.

UConn Health's expert surgeons are extensively trained in robotic surgery and fully equipped to carry out complex interventions.

Nurse Navigator

Alicja Paci

Alicja Paci, BSN, RN

Diagnosis, Ovarian, Endometrial, Cervical and Other Gynecologic Cancers, Prostate, Kidney, Bladder and Testicular Cancer

Phone: 860-505-9104
Email: paci@uchc.edu
Fax: 860-676-3437

Nurse Navigators are here to help you through your entire health journey, diagnosis through treatment.

Ovarian Cancer

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